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Skin Anatomy

The skin is the largest organ in the human body. It consists of two layers:

The Epidermis

The outer layer of the epidermis is the stratum corneum, a protective layer which consists of 15 to 40 layers of flattened skin cells or corneocytes that migrate up from the bottom layer of the epidermis.

The epidermis replaces itself about once a month. The stratum corneum serves as a barrier to protect the human body from external environmental factors.

Beneath the stratum corneum lie the keratinocytes, cells which form the building blocks of the epidermis. At the lowest level of the epidermis there is a row of cells called the basal cell layer. This layer contains basal cells which regenerate the major portion of the epidermis, as well as melanocytes, which produce the pigment melanin. Skin color is determined by the amount of melanin in the skin.

Also present are sensory nerve receptors and cells which are part of the immune system. The epidermis is the layer where most skin cancers arise.

The Dermis

The dermis consists of collagen and elastic fibers within a ground substance or matrix. Within the dermis are:

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